Professor Petrucci started her professional career as an Italian teaching assistant at Wesleyan University (CT) where she taught for a year. She continued teaching Italian as a second language at the University of California in Rome for three more years. After a two-year experience in Finmeccanica S.p.A. as an officer in the Environment, Health and Safety Department she began working at the International Projects and R&D Office of the Università degli Studi Guglielmo Marconi as a project manager.
She joined The American University of Rome in 2011 where she started off as the Administrative Assistant to the Provost Office. After two years, she moved on to the role of Director of the First Year Program and Coordinator of Special Programs. In October 2016, she took on the role of Director of First Year Experience and Outcomes Assessment.